Two key COVID-19 vaccines enter the final stages of trials before FDA approval

U.S. company Pfizer and BioNTech (German biotech) announced Monday that they have begun late-stage human trials for their COVID-19 vaccine. The first “Phase 3” trial in the U.S. has also begun with biotech company Moderna and the National Institute of Allergy and Infectious Diseases (part of the NIH) announcing that they will begin their trials at nearly 100 U.S. research sites, CNN reports. Both vaccines will be submitted to the FDA for approval after successful final-stage trials.

Moderna and the National Institutes of Health

Moderna and the NIH are expected to bring in about 30,000 adult volunteers to conduct final analysis of the safety of the SARS-CoV-2 vaccine that they have been developing. The primary goal is to confirm that the vaccine can prevent COVID-19 cases after two doses of the vaccine.

Read Also: COVID-19 patients no longer infectious after 10 days, CDC guidelines say

The Phase 1 trials, published in the New England Journal of Medicine, showed that the vaccine initiated a response from the immune system and was generally safe. However, there were also side effects such as fatigue, chills, headache, muscle pain, pain at the injection site. Phase 1 and Phase 2 trials were conducted on a smaller level and a lower variety of characteristics of people. The Moderna/NIH vaccine is one of 25 clinical studies in the world, according to the WHO.

Pfizer and BioNTech

Pfizer’s and BioNTech’s vaccine trial is considered to be in Phase 2/3, CNBC reports. Kathrin Jansen, head of vaccine research and development at Pfizer, says, “The initiation of the Phase 2/3 trial is a major step forward in our progress toward providing a potential vaccine to help fight the ongoing COVID-19 pandemic. Many steps have been taken towards this important milestone and we would like to thank all those involved for their extraordinary commitment.”

This vaccine is an mRNA vaccine, meaning it uses the messenger RNA to initiate an immune response from the body. Pfizer’s and BioNTech’s vaccine trial is also expected to include up to 30,000 participants between the age of 18 and 85. This trial is spread across 120 sites globally. The companies hope to supply 100 million doses by the end of 2020, and around 1.3 billion doses by the end of 2021, if the trials complete successfully.

Other companies like Johnson & Johnson and AstraZeneca are also developing COVID-19 vaccines. Johnson & Johnson said that it expects to begin late-stage human trials near the end of September while AstraZeneca said they are looking for volunteers in their late-stage trial, which is currently ongoing.

Do you want to publish on Apple News, Google News, and more? Join our writing community, improve your writing skills, and be read by hundreds of thousands around the world!

More from Health – News Landed

+ COVID-19 kills more men than women. This may be the reason why.
+ [UPDATE]: FDA warns 77 hand sanitizers may be toxic, avoid them

Popular Stories – News Landed

+ The center of our solar system is not the Sun, new animation shows
+ Thousands rush towards the airport as Vietnam evacuates 80,000 tourists from Da Nang

Related Stories

Another variant of the COVID-19 virus emerge in Washington

The pandemic is still seeking attention all over the country. The vaccine produced is efficacious, but there is no...

The UK is Leaving Lockdown – hopefully for good

In a long-awaited press briefing on Monday 22nd February, PM Boris Johnson revealed the cabinet's strategy to leaving the...

Featured Stories

NASA’s Perseverance rover is set to touchdown on the Martian surface this Thursday

This February has been a good month for Mars exploration. We recently heard the news about the Emirates Mars...

Scientists want Pablo Escobar’s hippos to be killed and here’s why

We all know Pablo Escobar was one of the notorious criminals of all time. The man who lived in...

Taylor Swift announces the release of re-recorded album, ‘Fearless’; dropped a new version of ‘Love Story

On Thursday (January 11), Taylor Swift announced to the world that she would be dropping the re-recorded version of...

High altitude Arctic Lakes and their link to climate change

Most lakes around the world play a crucial role in affecting the greenhouse concentrations of the atmosphere. In extreme...

People unlikely to suffer from thrombocytopenia after receiving COVID-19 vaccine

The COVID-19 situation has brought the entire research communities all over the world to focus on developing vaccines. As...

Noise pollution has found its way to deep oceans – A research finds

When we think of pollution created by human activity, the things that come into our mind are atmospheric pollution...