Researchers from the North Caucasus Federal University (NCFU), along with their US counterparts, have discovered a new anticancer substance that can be used against neuroblastoma, a cancer commonly found in the adrenal glands. The results of the research are published in the journal Organic & Biomolecular Chemistry.
“The researchers described the synthesis of a substance which will help humankind to fight neuroblastoma, one of the most dangerous types of cancer. Initially, the chemists were trying to obtain the compounds to fight COVID-19, however, the anticancer activity of these substances turned out to be much higher,” the NCFU press service told TASS on Tuesday.
The researchers used a method called the Aksenov reaction, discovered in 2010. The research was led by NCFU professors Nikolai Aksenov and Alexander Aksenov in collaboration with Texas State University.
“(The reaction) is based on introducing an amine group to an aromatic substance and is very promising,” Professor Alexander Aksenov was quoted as saying. The researchers say that this new finding will help lower the cost of therapy for cancer patients.
The research was financially supported by two grants from the Russian Foundation for Basic Research and the US National Institutes of Health.
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