Neglected tropical diseases (NTD) affect more than 1 billion people in the world. Mostly, the people live in poor countries of tropical and subtropical becomes the victim. Some of the NTDs include schistosomiasis, onchocerciasis, lymphatic filariasis, leishmaniasis, Chagas disease. For instance, the causative agent like Schistosome haematobium and S. mansoni for Schistosomiasis, Onchocerca volvulus for river blindness, Wuchereria bancrofti for elephantiasis are some commonly known.
There are certain drugs in practice to treat all the NTDs. This process involves repeated treatments, which can result in drug resistance. However, to tackle it, the researchers in Ghana developed traditional medicines in an attempt to reduce the infection in those people. As these NTDs remain endemic in that area, it may definitely help the population.
They produced 15 traditional medicines from the herbs and allowed them to screen in the laboratory. The crude extracts from the medicinal plants were about to check for treating the NTDs. Out of several extracts, NTD-B4-DCM and NTD-B7-DCM had significant performance against S. mansoni. It reduced the locomotor activity of the worms by 78.4% and 84.3%. Also, NTD-B2-DCM was having the ability to kill 100% of males and above 60% of Onchocerca onchengi worms.
Besides, eight crude extracts showed to act against trypanosomes. These traditional remedies bring hope for all of us to provide sustainable life all through our struggles.
Source: Medical Xpress
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