Researchers insight on how SARS-CoV-2 variants escape from immune response

The COVID-19 pandemic is still creating apprehension even after the development of several vaccines and antiviral therapy. Mutations occurring in SARS-CoV-2 enable the virus to escape from neutralizing antibodies. These mutations happen at a particular area called the ” Receptor binding site” on the spike protein of the virus.

The study

SARS-CoV-2 ” variants of concern’ include the UK’s B.1.1.7, South Africa’s B.1.351 variants, Brazil’s P.1, and India’s B.1.617. In this study, researchers focused on three mutations in the receptor-binding site of spike protein: K417N, E484K, and N501Y of SARS-CoV-2. Perhaps, these mutations are in the receptor-binding site where the virus attaches to the host cells. The researchers also tested representative antibodies that target the general areas in and around the receptor-binding protein. Also, they found that many of the antibodies lose their ability to neutralize the virus when these mutations are present. Therefore using structural imaging techniques, the researchers were able to understand how virus-neutralizing antibodies target two other areas outside the receptor-binding sites that were unaffected by these 3 mutations.

This study helps in the production of future vaccines and antibody-based treatments. It would provide protection to the SARS-CoV-2 variants and could help in the near future.

Do you want to publish on Apple News, Google News, and more? Join our writing community, improve your writing skills, and be read by hundreds of thousands around the world!

+ The Covid-19 booster shot might be required to further strengthen the Immune system…
+ Ariana Grande weds Dalton Gomez in an intimate ceremony

Related Stories

Boris Johnson and Rishi Sunak reverse decision to avoid self-isolation following ping by NHS contact tracing

Following the Health Secretary's diagnosis with COVID-19, the Prime Minister and Chancellor were notified by NHS Test and Trace...

Singapore Road map to become New normal

The deadly coronavirus may never go away but it is possible to live normally with it in our midst....

Featured Stories

Will Telosa be the “City of the Future” by 2030?

Shenzhen, China was a sleepy fishing village in 1979. A mere forty years later, it is one of the...

Low-cost lead adsorbing water filter designed by Indian students

Two students from India have designed a low-cost lead water filter that can be made with locally sourced materials....

Make it Rain! Dubai uses drones to conjure rain from the skies

You can order food, hail a driver, and even find a spouse with the click of a button; but...

Physicists have created the world’s thinnest magnet. Just one atom thick!

Can you guess the size of the thinnest magnet? It is just one atom thick. Scientists from the University of...

Boris Johnson and Rishi Sunak reverse decision to avoid self-isolation following ping by NHS contact tracing

Following the Health Secretary's diagnosis with COVID-19, the Prime Minister and Chancellor were notified by NHS Test and Trace...

India is one of the largest producers of COVID vaccine and yet faces major internal shortages

The worsening situation in India finally gained some stabilization around September 2020. Usually, when things start getting better, people...